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Yapan Bio has integrated capabilities from early stage research, Process Development & scale-up to Process Characterization and GMP manufacturing for Human Clinical Studies.

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  • Rocker, Stirred Tank and Adherent Cell Bioreactors
     

  • Method Qualification and Stability studies
     

  • Upstream: Bioreactors / fermenters, disposable systems, fed-batch, perfusion, expression kinetics
     

  • Downstream: Centrifugation, tangential flow filtration (UF/DF), Depth filtration, Chromatography
     

  • Up to 200L Stirred bioreactor scale 
     

  • Aseptic formulation/fill/finish (Liquid in Vials)

DEVELOPMENT AND MANUFACTURING CAPABILITIES

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  • Process Development and Optimization
     

  • Process Characterization
     

  • Scale-up and Technology Transfer
     

  • GMP Manufacturing

EXPERTISE

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Vaccines

  • Recombinant Vaccines (Protein antigens, Virus Like Particles, Nano-Particles etc.)

  • RNA/DNA Vaccines

  • Whole Cell and Live (attenuated) Vaccines 

Biologics/Biotherapeutics

  • Gene Therapy

    • Oncolytic Viruses 

    • Vectors (Viral, Non-viral Plasmid, Naked DNA) etc.

  • Monoclonal Antibodies

  • Therapeutic proteins and other complex biologics

TECHNOLOGIES

SUSPENSION CELL CULTURES

VIRAL CULTURE

CHROMATOGRAPHY

ADHERENT CELL CULTURES

BACTERIAL FERMENTATION

FILTRATION

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