Yapan Bio has integrated capabilities from early stage research, Process Development & scale-up to Process Characterization and GMP manufacturing for Human Clinical Studies.

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• Rocker, Stirred Tank and Adherent Cell Bioreactors
   

• Method Qualification and Stability studies
   

• Upstream: Bioreactors / fermenters, disposable systems, fed-batch, perfusion, expression kinetics
   

• Downstream: Centrifugation, tangential flow filtration (UF/DF), Depth filtration, Chromatography
   

• Up to 200L Stirred bioreactor scale 
   

• Aseptic formulation/fill/finish (Liquid in Vials)

DEVELOPMENT AND MANUFACTURING CAPABILITIES

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• Process Development and Optimization
   

• Process Characterization
   

• Scale-up and Technology Transfer
   

• GMP Manufacturing

EXPERTISE

Vaccines

• Recombinant Vaccines (Protein antigens, Virus Like Particles, Nano-Particles etc.)

• RNA/DNA Vaccines

• Whole Cell and Live (attenuated) Vaccines 

TECHNOLOGIES

SUSPENSION CELL CULTURES

VIRAL CULTURE

CHROMATOGRAPHY

ADHERENT CELL CULTURES

BACTERIAL FERMENTATION

FILTRATION